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Synthesis Reference(s) |
Journal of the American Chemical Society, 78, p. 3425, 1956 DOI: 10.1021/ja01595a044Organic Syntheses, Coll. Vol. 2, p. 531, 1943Synthesis, p. 54, 1988 |
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Purification Methods |
Crystallise the acid from water or from *benzene containing 5% diethyl ether. [Beilstein 1 IV 2003.] |
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Definition |
ChEBI: An alpha,omega-dicarboxylic acid that is pentane with two carboxylic acid groups at positions C-1 and C-5. |
InChI:InChI=1/C7H12O4/c8-6(9)4-2-1-3-5-7(10)11/h1-5H2,(H,8,9)(H,10,11)/p-2
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1-(2-methoxyvinyl)benzene


(E)-2-benzylidenecycloheptanone


heptanedioic acid


benzaldehyde
| Conditions | Yield |
|---|---|
|
With ozone; In diethyl ether; at -70 ℃;
|
65% 17% |

1-(2-methoxyvinyl)benzene

![2-[1-(2-Trifluoromethyl-phenyl)-meth-(E)-ylidene]-cycloheptanone](/upload/2025/4/edd05d00-a0ef-4abb-9e16-a0f10934e196.png)
2-[1-(2-Trifluoromethyl-phenyl)-meth-(E)-ylidene]-cycloheptanone


heptanedioic acid


benzaldehyde
| Conditions | Yield |
|---|---|
|
With ozone; In diethyl ether; at -70 ℃;
|
60% 17% |

3-(tetrahydrofuran-2-yl)propanoic acid

oxacycloheptadec-8-en-2-one

1,5-dibromo-pentane

sodium cyanide

dimethyl 1,7-heptanedioate

dipropyl pimelate

heptanedioic acid di-p-tolyl ester

7-ethoxy-7-oxoheptanoic acid